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    Preventing postnatal transmission of HIV-1 through breast-feeding: modifying infant feeding practices

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    Date
    2004-02
    Author
    Rollins, N
    Meda, N
    Becquet, R
    Coutsoudis, A
    Humphrey, J
    Jeffrey, B
    Kanshana, S
    Kuhn, L
    Leroy, V
    Mbori-Ngacha, DA
    McIntyre, J
    Newell, ML
    Ghent IAS Working Group on HIV in Women and Children.
    Type
    Article
    Language
    en
    Metadata
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    Abstract
    Approaches to reducing or preventing the risk of postnatal transmission through breast-feeding include the avoidance of all breast-feeding and the use of exclusive replacement feeds or exclusive breast-feeding for a limited duration with early and rapid cessation of breast-feeding around 4-6 months of age. The efficacy and safety of the latter approach have not been established and studies are in progress to provide further information. In addition, inactivation of HIV in breast milk would allow breast-feeding to continue while reducing the risk of postnatal transmission of HIV and may be usefully applied in certain circumstances, such as for premature infants or while a mother recovers from mastitis. In this review, experience is reported from clinical trials or studies additional to their main objective of assessing rates and risk factors for mother-to-child transmission. This may inform policy, programming, and training options and may be especially valuable in the absence of conclusive data on the efficacy of the interventions to be applied during the breast-feeding period.
    URI
    http://www.ncbi.nlm.nih.gov/pubmed/14722453
    http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30518
    Citation
    J Acquir Immune Defic Syndr. 2004 Feb 1;35(2):188-95.
    Publisher
    University of Nairobi.
     
    Africa Centre for Health and Population Studies, Mtubatuba, South Africa
     
    Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya
     
    Subject
    Acquired Immunodeficiency Syndrome
    prevention & control
    transmission
    Breast Feeding
    adverse effects
    Disease Transmission
    Vertical
    prevention & control
    Female
    Humans
    Infant
    Milk
    Human
    virology
    Pregnancy
    Safety
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    • Faculty of Health Sciences (FHS) [10067]

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