Preventing postnatal transmission of HIV-1 through breast-feeding: modifying infant feeding practices
Date
2004-02Author
Rollins, N
Meda, N
Becquet, R
Coutsoudis, A
Humphrey, J
Jeffrey, B
Kanshana, S
Kuhn, L
Leroy, V
Mbori-Ngacha, DA
McIntyre, J
Newell, ML
Ghent IAS Working Group on HIV in Women and Children.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Approaches to reducing or preventing the risk of postnatal transmission through breast-feeding include the avoidance of all breast-feeding and the use of exclusive replacement feeds or exclusive breast-feeding for a limited duration with early and rapid cessation of breast-feeding around 4-6 months of age. The efficacy and safety of the latter approach have not been established and studies are in progress to provide further information. In addition, inactivation of HIV in breast milk would allow breast-feeding to continue while reducing the risk of postnatal transmission of HIV and may be usefully applied in certain circumstances, such as for premature infants or while a mother recovers from mastitis. In this review, experience is reported from clinical trials or studies additional to their main objective of assessing rates and risk factors for mother-to-child transmission. This may inform policy, programming, and training options and may be especially valuable in the absence of conclusive data on the efficacy of the interventions to be applied during the breast-feeding period.
URI
http://www.ncbi.nlm.nih.gov/pubmed/14722453http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30518
Citation
J Acquir Immune Defic Syndr. 2004 Feb 1;35(2):188-95.Publisher
University of Nairobi. Africa Centre for Health and Population Studies, Mtubatuba, South Africa Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya
Subject
Acquired Immunodeficiency Syndromeprevention & control
transmission
Breast Feeding
adverse effects
Disease Transmission
Vertical
prevention & control
Female
Humans
Infant
Milk
Human
virology
Pregnancy
Safety
Collections
- Faculty of Health Sciences (FHS) [10377]