Evaluation of five immunodiagnostic techniques in echinococcosis patients

Date
1981Author
AK, Chemtai
TR, Bowry
Z, Ahmad
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Double diffusion (DD), indirect haemagglutination (IHA), immunoelectrophoresis (IEP), latex agglutination (LA), and complement fixation (CF) tests were evaluated for sensitivity and specificity in the diagnosis of 141 surgically-proven Turkana echinococcosis patients and 10 controls. The overall sensitivities for the tests were: IHA, 86.7%; LA, 53.3%; CF, 63.3%; DD, 55.0%; IEP, 55.0%. LA and CF tests produced a high number of false positive results; IHA gave a false positive result in 10% of cases; no false positives were obtained with IEP and DD. A combination of the latter three tests would therefore offer the best chance of detecting specific anti-Echinococcus antibodies, with an average sensitivity of 62.7%. The possible reasons for the relatively high incidence of false negative values are discussed.
URI
http://www.ncbi.nlm.nih.gov/pubmed/6976237http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30739
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396102/
Citation
Bull World Health Organ. 1981; 59(5): 767–772Publisher
University of Nairobi Department of Infectious Diseases
Collections
- Faculty of Health Sciences (FHS) [10227]