Illness during pregnancy and bacterial vaginosis are associated with in-utero HIV-1 transmission
View/ Open
Date
2010-01Author
Farquhar, C
Mbori-Ngacha, DA
Overbaugh, J
Wamalwa, D
Harris, J
Bosire, R
John-Stewart, G
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
HIV-1 transmission in utero accounts for 20-30% of vertical transmission events in breast-feeding populations. In a prospective study of 463 HIV-1-infected mothers and infants, illness during pregnancy was associated with 2.6-fold increased risk of in-utero HIV-1 transmission [95% confidence interval (CI) 1.2-5.8] and bacterial vaginosis with a three-fold increase (95% CI 1.0-7.0) after adjusting for maternal HIV-1 viral load. Interventions targeting these novel risk factors could lead to more effective prevention of transmission during pregnancy
URI
http://www.ncbi.nlm.nih.gov/pubmed/19952542http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30785
Citation
AIDS. 2010 Jan 2;24(1):153-5Publisher
University of Nairobi. Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya
Collections
- Faculty of Health Sciences (FHS) [10377]