dc.contributor.author | Nsanze, H | |
dc.contributor.author | D'Costa, LJ | |
dc.contributor.author | Owili, DM | |
dc.contributor.author | Ilako, F | |
dc.contributor.author | Ndinya-Achola, JO | |
dc.contributor.author | Piot P | |
dc.date.accessioned | 2013-06-11T08:12:29Z | |
dc.date.available | 2013-06-11T08:12:29Z | |
dc.date.issued | 1984-12 | |
dc.identifier.citation | Sex Transm Dis. 1984 Oct-Dec;11(4 Suppl):376-8. | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/6441281 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/31224 | |
dc.description.abstract | The efficacy of a single 2.5-g dose of thiamphenicol against infection with penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) or non-penicillinase-producing strains (non-PPNG) was studied in a two-phase clinical trial in Nairobi. The first phase included men who had had a urethral discharge for less than seven days, were infected with either PPNG or non-PPNG, and had not received previous treatment. The second phase included men with PPNG infections that had not responded to treatment with penicillin. The overall cure rate (determined by follow-up examinations and cultures three and ten days after treatment) was 90.6% in the first phase of the study and 92.1% in the second phase. A second 2.5-g dose of thiamphenicol was administered to four of the six patients in the second phase whose cultures yielded gonococci after the initial dose; the infections of all four patients were cured. The results of disk diffusion tests of gonococcal isolates did not correlate well with the outcome of treatment. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi, | en |
dc.title | Treatment of gonorrhea with single-dose thiamphenicol in Kenya | en |
dc.type | Article | en |
local.publisher | Department of Medicine | en |