Pharmacokinetics of pindolol in Kenyan Africans.
Abstract
The pharmacokinetics of pindolol was studied in 8 normal Africans following administration of a single oral 10 mg dose. The mean peak concentration was 30.2 +/- 5.0 ng X ml-1, the mean half-life (t1/2) of the elimination phase was 3.4 +/- 1.1 h, and the total body clearance was 628 +/- 13 ml X min-1. The apparent volume of distribution was 3.0 +/- 1.31 X kg-1. The values are the same as those reported in Europeans.
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/6628532http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/31231
Citation
Eur J Clin Pharmacol. 1983;25(3):425-6Publisher
Univesity of Nairobi Department of Medicine
Collections
- Faculty of Health Sciences (FHS) [10378]