Natural course of delta superinfection in chronic hepatitis B virus-infected patients: histopathologic study with multiple liver biopsies.
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Date
1986Author
de cock, km
Govindarajan, AG
Redeker, S
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
We evaluated the natural course of delta superinfection in patients with chronic B viral hepatitis by examining serial liver biopsy specimens from 23 patients. The mean follow-up period was 2.5 years, and the average number of liver biopsies per patient was 2.8. The striking features were: (i) the prolonged acute hepatitis-like necroinflammatory activity (mean = 15 months) following acute delta hepatitis and (ii) rapid progression to severe forms of liver disease within a mean interval of 24 months from the onset of delta superinfection. Although there was a high frequency of stainable delta antigen (90%) in these liver biopsy specimens, there was no correlation between the degree of positivity and the histopathological changes.
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/3525368http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/31706
Citation
Hepatology. 1986 Jul-Aug;6(4):640-4.Publisher
University of Nairobi College of Humanities Sciences
Collections
- Faculty of Health Sciences (FHS) [10387]