| dc.contributor.author | Campbell, MS, | |
| dc.contributor.author | Kahle, EM | |
| dc.contributor.author | Celum, C | |
| dc.contributor.author | Lingappa, JR | |
| dc.contributor.author | Kapiga, S | |
| dc.contributor.author | Mujugira, A | |
| dc.contributor.author | Mugo, NR | |
| dc.contributor.author | Fife, KH | |
| dc.contributor.author | Mullins, JI | |
| dc.contributor.author | Baeten, JM | |
| dc.date.accessioned | 2013-06-12T11:16:44Z | |
| dc.date.available | 2013-06-12T11:16:44Z | |
| dc.date.issued | 2013 | |
| dc.identifier.citation | Plasma viral loads during early HIV-1 infection are similar in subtype C- and non-subtype C-infected African seroconverters. Campbell MS, Kahle EM, Celum C, Lingappa JR, Kapiga S, Mujugira A, Mugo NR, Fife KH, Mullins JI, Baeten JM; J Infect Dis. 2013 Apr;207(7):1166-70. doi: 10.1093/infdis/jit015. Epub 2013 Jan 11. | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/23315322 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/32180 | |
| dc.description.abstract | Recent data suggest that infection with human immunodeficiency virus type 1 (HIV-1) subtype C results in prolonged high-level viremia (>5 log10 copies/mL) during early infection. We examined the relationship between HIV-1 subtype and plasma viremia among 153 African seroconverters. Mean setpoint viral loads were similar for C and non-C subtypes: 4.36 vs 4.42 log10 copies/mL (P = .61). The proportion of subtype C-infected participants with viral loads >5 log10 copies/mL was not greater than the proportion for those with non-C infection. Our data do not support the hypothesis that higher early viral load accounts for the rapid spread of HIV-1 subtype C in southern Africa. | en |
| dc.language.iso | en | en |
| dc.title | Plasma viral loads during early HIV-1 infection are similar in subtype C- and non-subtype C-infected African seroconverters. | en |
| dc.type | Article | en |
| local.publisher | Medicine, University of Washington, Seattle, WA 98195, USA | en |
