Absorption of controlled release morphine sulphate in the immediate postoperative period.
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The absorption of morphine sulphate, given orally as a controlled release preparation, was studied in 10 patients who had undergone peripheral vascular surgery with a standard opioid-based general anaesthetic technique. Serum morphine concentrations were measured (high pressure liquid chromatography) every 2 h for the first 16 h after surgery and the results were strongly suggestive of a decrease in the rate of absorption of morphine in this situation.
CitationBr J Anaesth. 1986 Aug;58(8):868-71.
university of nairobicollege of health science