| dc.contributor.author | Mugweru, J | |
| dc.contributor.author | Okindo, E | |
| dc.contributor.author | Odongo, H | |
| dc.contributor.author | Onyango, D.W | |
| dc.contributor.author | Wango, E.O | |
| dc.date.accessioned | 2013-06-14T14:31:57Z | |
| dc.date.available | 2013-06-14T14:31:57Z | |
| dc.date.issued | 1997 | |
| dc.identifier.citation | Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology Volume 118, Issue 3, November 1997, Pages 381–386 | en |
| dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0742841397001047 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/34054 | |
| dc.description.abstract | Male rats were divided into six groups of five rats each. Rats were injected subcutaneously with different concentrations of heptachlor for 2 weeks. Heptachlor at all doses significantly suppressed plasma testosterone levels (P < 0.05). Plasma luteinizing hormone (LH) (P < 0.01) and cortisol (P < 0.02) levels were significantly elevated in heptachlor-treated rats as compared to corn oil–treated controls. LH and testosterone levels showed strong correlation (r = 0.69, P < 0.05). The testes in rats treated with 25 mg/kg body weight of heptachlor showed some pathological changes. We conclude that heptachlor causes adverse effects on several male reproductive parameters in rats. | en |
| dc.language.iso | en | en |
| dc.publisher | Elsevier, | en |
| dc.subject | Heptachlor; male rats; luteinizing hormone; testosterone; cortisol; testis; reproduction | en |
| dc.title | In Vitro Production of Testosterone and Plasma Levels of Luteinising Hormone, Testosterone and Cortisol in Male Rats Treated with Heptachlor | en |
| dc.type | Article | en |
| local.publisher | Reproductive Biology Unit, University of Nairobi, Nairobi, Kenya | en |
