| dc.contributor.author | Yenesew, Abiy | |
| dc.contributor.author | Twinomuhwezi, Hannington | |
| dc.contributor.author | Kabaru, Jacques M | |
| dc.contributor.author | Akala, Hoseah M | |
| dc.contributor.author | Kiremire, Bernard T | |
| dc.contributor.author | Heydenreich, Matthias | |
| dc.contributor.author | Peter, Martin G | |
| dc.contributor.author | Eyase, Fredrick L | |
| dc.contributor.author | Waters, Norman C | |
| dc.contributor.author | Walsh, Douglas S | |
| dc.date.accessioned | 2013-06-15T12:15:55Z | |
| dc.date.issued | 2009 | |
| dc.identifier.citation | Bull. Chem. Soc. Ethiop. 2009, 23(3), 409-414. | en |
| dc.identifier.uri | http://www.ajol.info/index.php/bcse/article/view/47665/34042 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/34468 | |
| dc.description.abstract | From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new
flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin
and rotenone were identified. The structures were determined on the basis of spectroscopic evidence. Lupinfolin
showed moderate in vitro antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquineresistant) strains of Plasmodium falciparum. The different parts of this plant showed larvicidal activities against
Aedes aegypti and rotenoids were identified as the active principles. | en |
| dc.language.iso | en | en |
| dc.subject | Derris trifoliata | en |
| dc.subject | Leguminosae | en |
| dc.subject | Flavanone | en |
| dc.subject | (S)-Lupinifolin 4´-methyl ether | en |
| dc.subject | Lupinifolin | en |
| dc.subject | Antiplasmodial | en |
| dc.subject | Rotenoid | en |
| dc.subject | Larvicide | en |
| dc.subject | Aedes aegyp | en |
| dc.title | Antiplasmodial and larvicidal flavonoids from Derris trifoliata | en |
| dc.type | Article | en |
| local.publisher | Department of Chemistry, University of Nairobi, | en |
| local.publisher | School of Biological Sciences, University of Nairobi | en |
| local.publisher | United States Army Medical Research Unit-Kenya, MRU 64109, APO, AE 09831-4109, USA | en |
| local.publisher | Department of Chemistry, Makerere University, P.O. Box 7062, Kampala, Uganda | en |
| local.publisher | Institut für Chemie, Universität Potsdam, P.O. Box 60 15 53, D-14415 Potsdam, Germany | en |
