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Detection Of Serum Hbv-dna By Molecular Hybridisation. Correlation With Hbeag/anti-hbe Status, Racial Origin, Liver Histology And Hepatocellular Carcinoma.

dc.contributor.authorKarayiannis, P
dc.contributor.authorFowler, MJ
dc.contributor.authorLok, AS
dc.contributor.authorGreenfield, C
dc.contributor.authorMonjardino, J
dc.contributor.authorThomas, HC
dc.date.accessioned2013-06-18T09:50:16Z
dc.date.available2013-06-18T09:50:16Z
dc.date.issued1985
dc.identifier.citationJ Hepatol. 1985;1(2):99-106.en
dc.identifier.urihttp://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/2997321
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35514
dc.description.abstractThe relationship of the presence of hepatitis B virus (HBV) DNA in serum, a measure of HBV-replication, to HBeAg/anti-HBe status has been examined. In Northern Europe, there is a strong positive correlation between the presence of HBV-DNA and HBe antigenaemia and a negative correlation with the presence of anti-HBe. These associations are less marked in patients from Southern Europe, Africa, the Middle and Far East. When HBV-DNA is present in the serum of anti-HBe carriers, it is usually associated with the presence of severe liver disease or carcinoma. Forty percent of patients with hepatocellular carcinoma had evidence of continuing HBV replication.en
dc.language.isoenen
dc.publisherUniversity Of Nairobien
dc.titleDetection Of Serum Hbv-dna By Molecular Hybridisation. Correlation With Hbeag/anti-hbe Status, Racial Origin, Liver Histology And Hepatocellular Carcinoma.en
dc.typeArticleen
local.publisherFaculty Of Medicineen


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