dc.contributor.author | Fröhlich, SJ | |
dc.contributor.author | Miño de Kaspar, H | |
dc.contributor.author | Grasbon, T | |
dc.contributor.author | Möhring, C | |
dc.contributor.author | Klauss, V | |
dc.contributor.author | Kampik, A | |
dc.date.accessioned | 2013-06-18T12:53:54Z | |
dc.date.available | 2013-06-18T12:53:54Z | |
dc.date.issued | 1999 | |
dc.identifier.citation | Ophthalmologe. 1999 Jul;96(7):459-64. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/10479898 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35677 | |
dc.description.abstract | PURPOSE:
The study presented differentiates between the aetiological agents of bacterial keratitis in patients with and without a history of contact lens wear. Based on these results, recommendations are given for optimal antibiotic primary therapy.
PATIENTS AND METHODS:
Swabs and corneal scrapings were taken from 218 patients referred to the University Eye Hospital in Munich with a diagnosis of bacterial keratitis from 1989 to 1997. Ninety-two of these patients had a history of contact lens wear; 126 had none. The germs were isolated and identified by staining and microscopy. Observing polymicrobial growth in 51 patients, a total of 275 germs was isolated.
RESULTS:
The most frequent pathogens were Staphylococcus epidermidis (44%), S. aureus (18%), Streptococcus spp. (10%), Propionibacterium acnes (7%) and Pseudomonas aeruginosa (6%). Gram-negative germs were nearly exclusively isolated from contact lens wearers, gram-positive germs were predominant in non-contact lens wearers.
CONCLUSION:
Keratitis in patients with a history of contact lens wear is often caused by aggressive gram-negative germs. Those cases should immediately be treated with quinolones and erythromycin. In keratitis caused by gram-positive pathogens, a combination with aminoglycosides and erythromycin is sufficient. | en |
dc.language.iso | en | en |
dc.title | Bacterial keratitis. Microbiological analysis as a principle for therapeutic recommendations. | en |
dc.type | Article | en |
local.publisher | Department of Ophthalmology, College of Health Sciences, University of Nairobi | en |