Effects of wisanine and dihydrowisanine on aggressive behaviour in chicks.
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Date
1993-11Author
Ayitey-Smith, E
Addae-Mensah, I
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The effects of wisanine and dihydrowisanine were studied on stereotyped and aggressive behaviour induced by apomorphine (0.5 mg/kg s.c.) in chicks. Pretreatment of chicks with wisanine (0.3-0.6 g/kg i.p.) and dihydrowisanine (0.2-0.4 g/kg i.p.) dose dependently antagonised fighting episodes and pecking of the chick's own feet and those of other chicks. It has been suggested that the antagonism is due to dopaminergic receptor blockade and demonstrates the antipsychotic effect of these drugs.
URI
http://www.ncbi.nlm.nih.gov/pubmed/6686821http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/36188
Citation
Eur J Pharmacol. 1983 Nov 11;95(1-2):139-41.Publisher
University of Nairobi School of medicine,University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10377]