Bronchoscopic Study On Aetiology Of Chronic Cough In HIV-infected Adults With Negative Sputum Smears For Mycobacterium Tuberculosis At Kenyatta National Hospital, Nairobi
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Date
2006Author
Siika, AM
Chakaya, JM
Revathi, G
Mohamed, SS
Bhatt, KM
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
OBJECTIVE:
To establish the aetiology of chronic cough in HIV-infected patients with negative sputum smears for Acid Fast Bacilli (AFB).
DESIGN:
A cross-sectional descriptive study.
SETTING:
Kenyatta National Hospital, a tertiary referral centre in Kenya
SUBJECTS:
Sixty five HIV-infected adults presenting with chronic cough and negative sputum smears for AFBs.
RESULTS:
Sixty-two patients were included in the final analysis. Aetiology of chronic cough was established in 42 (68%) patients. Pneumocystis jiroveci, bacterial pneumonia and Mycobacterium tuberculosis were diagnosed in 22 (35.5%), 17 (27.4%) and 14 (22.5%) patients respectively. Majority (98%) of patients with a diagnosis had multiple causes established in them. Ciprofloxacin had activity against 91% of the isolated organisms while Penicillin was active against 35% only.
CONCLUSION:
This study documents Pneumocystis jiroveci pneumonia as a common cause of morbidity in a subset of HIV infected patients with chronic cough and negative sputum smears for AFB in Kenya.
URI
http://profiles.uonbi.ac.ke/kirnabhatt/publications/bronchoscopic-study-aetiology-chronic-cough-hiv-infected-adults-negative-spuhttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/37082
Citation
East Afr Med J. 2006 Jun;83(6):295-305.Publisher
University of Nairobi Department of Medicine, Moi University School of Medicine
Collections
- Faculty of Health Sciences (FHS) [10378]