dc.contributor.author | Ongeti, K | |
dc.contributor.author | Saidi, H | |
dc.contributor.author | Ogeng'o, Julius A | |
dc.date.accessioned | 2013-06-21T11:34:30Z | |
dc.date.available | 2013-06-21T11:34:30Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Ongeti K., Saidi H. and Ogeng’o J.;2012. Non Expression Of Androgen Receptors In The Human Carotid Artery. Anatomy Journal Of Africa. : Journal Of Morphological Sciences | en |
dc.identifier.uri | http://jms.org.br/PDF/v29n3a06.pdf | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/37484 | |
dc.description.abstract | Androgens and oestrogens have been implicated in the noted gender differences in the increasing intimal
medial thickness. Oestrogens are protective in females while the role of androgens as male disadvantage
remains in conflict. There have been reports that androgens are protective while other reports suggest they
are bane. The distribution of androgen receptors in the carotid intimal medial thickness may help explain this
propensity. Thirty six samples from the proximal, middle and distal carotid artery segments and three sections
of prostate gland from three different men were collected within 48 hours of demise were processed for
routine light microscopy and immunohistochemistry. The prostate samples were mounted next to the carotid
artery samples on the same slide for immunohistochemical staining. They were stained using anti-human
mouse androgen receptor monoclonal antibody (AR318) for androgen receptors. All prostate control samples
stained for androgen receptors. Androgen receptors were not expressed in any of the carotid arterial walls. The
carotid intimomedial thickness is not influenced by the presence of androgen receptors. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.subject | androgen receptors, carotid intimal medial thickness | en |
dc.title | Non-expression of androgen receptors in the carotid intimal medial zone | en |
dc.type | Article | en |
local.publisher | Department of Human Anatomy, University of Nairobi | en |