Evaluation of the antimicrobial and antioxidant properties of extracts of Mondia whytei roots
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Date
2012Author
Mayunzu, Oscar
Shitanda, Douglas
Okalebo, Faith
Simiyu, Lidya
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Extracts of Mondia whytei (M. whytei) root barks were screened for their
inhibitory effects against Staphylococcus aureus (S. aureus) (ATCC 25923),
Escherichia coli (E. coli) 0157:H7 (PSSCMI 0032), Bacillus subtilis, Candida
albicans and Aspergillus niger were used as test organisms. From the results it
was concluded that activity varied with the solvent used. Contrary to previous
reports, the plant seems to lack significant antibacterial activity except against E.
coli. The popularity of a herbal recipe is not always a measure for its potency.
However, M. whytei had antifungal activity since the ethanol and methanol
extracts showed significant activity against the tested strains of fungi. The
antioxidant activity of the extracts was also evaluated using the DPPH free radical
scavenging assay. M. whytei exhibited substantial inhibition of the DPPH activity
with EC50 of 413mg/l for the crude extracts. This antioxidant activity of the crude
extracts can be attributed to the presence of 2-Hydroxy-4-Methoxybenzaldehyde
that is a known antioxidant in the root extracts
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http://www.ann.ugal.ro/tpa/Annals%202011/vol%202/3%20Mayunzu%20et%20al.pdfhttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/38296
Citation
Annals of the University Dunarea de Jos of Galati. Fascicle VI : Food Technology Volume/Issue v.35(2)Publisher
Galati University Press Department Of Pharmacology and Pharmacognosy, School Of Pharmacy Kenya Forestry Research Institute,Nairobi, Kenya Jomo Kenyatta University of Agriculture and Technology. Nairobi, Kenya
Collections
- Faculty of Health Sciences (FHS) [10377]