A new immunostimulatory complex (PICKCa) in experimental rabies: antiviral and adjuvant effects.
View/ Open
Date
1993Author
Lin HX.
Gontier Christopher Stuart.
Saron MF.
Perrin P.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The activity of an immunostimulatory complex (PICKCa) which is widely used against several human diseases in China was tested in experimental rabies prophylaxis. PICKCa protected mice against peripheral infection with both fixed and wild rabies strains. It also enhanced the protective activity of an experimental rabies vaccine injected either before or after rabies infection. PICKCa enhanced both non-specific immune responses and specific immunity including antibody production and cell mediated immunity as assessed by interleukin-2 production.
URI
http://www.ncbi.nlm.nih.gov/pubmed/7688505http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/38394
Citation
Lin HX, Gontier C, Saron MF, Perrin P.,A new immunostimulatory complex (PICKCa) in experimental rabies: antiviral and adjuvant effects.,Arch Virol. 1993;131(3-4):307-19.Publisher
University of Nairobi, Department of Human Pathology,
Collections
- Faculty of Health Sciences (FHS) [10377]