dc.contributor.author | Sack, DA | |
dc.contributor.author | Kaminsky, DC | |
dc.contributor.author | Sack, RB | |
dc.contributor.author | Wamola, IA | |
dc.contributor.author | Orskov, F | |
dc.contributor.author | Orskov, I | |
dc.contributor.author | Slack, RC | |
dc.contributor.author | Arthur, RR | |
dc.contributor.author | Kapikian, AZ | |
dc.date.accessioned | 2013-06-25T12:32:30Z | |
dc.date.available | 2013-06-25T12:32:30Z | |
dc.date.issued | 1977-08 | |
dc.identifier.citation | Johns Hopkins Med J. 1977 Aug;141(2):63-70. | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/196131 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/39746 | |
dc.description.abstract | Travelers' diarrhea was studied prospectively in a group of 39 American Peace Corps Volunteers (PCVs) during their first five weeks in Kenya. Twenty-seven developed diarrheal disease and 12 remained well. Multiple episodes were documented in 11 of the symptomatic volunteers. Enterotoxigenic Escherichia coli of many serotypes producing heat-labile and/or heat-stable enterotoxin were isolated from 17 of the 27 volunteers with diarrhea and from 1 of the 12 well volunteers. The enterotoxigenic E. coli were more likely to be antibiotic sensitive than the non-enterotoxigenic E. coli. A serum antibody rise to the heat-labile toxin (LT) was detected in six symptomatic volunteers, five of whom had a positive culture for LT-producing E. coli, and from one asymptomatic, culture negative volunteer. Salmonella cubana was isolated from two volunteers, and three volunteers had serologic evidence of infection with human reovirus-like (rotavirus) agent. This study confirms the role of enterotoxigenic E. coli as a major cause of travelers' diarrhea and suggests that the disease is similar in widely separated geographic areas. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | Enterotoxigenic Escherichia coli diarrhea of travelers: a prospective study of American Peace Corps volunteers | en |
dc.type | Article | en |
local.publisher | College of Health Sciences,University of Nairobi | en |