Prevalence of vulvovaginal candidiasis and susceptibility to fluconazole in women.
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Date
2012Author
Bauters, TG
Dhont, MA
Nelis, HJ.
Temmerman, M
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
OBJECTIVE:
The purpose of this study was to determine the prevalence of vaginal colonization by Candida with the use of a rapid detection method, to examine the determinants of vaginal candidiasis, and to evaluate susceptibility for fluconazole.
STUDY DESIGN:
Vaginal swabs were collected from unselected women at the outpatient clinic of the Department of Obstetrics and Gynecology. A differentiation was made between patients with a positive and a negative potassium hydroxide examination.
RESULTS:
Six hundred twelve women were recruited, of whom 39 women (6.3%) had clinical candidiasis. The overall rate of yeast colonization was 20.1%. Candida albicans was isolated most frequently(68.3%), followed by C glabrata (16.3%) and C parapsilosis (8.9%). Clinical candidiasis was related positively with the state of estrogen impregnation. In vitro susceptibility testing by the National Committee for Clinical Laboratory Standards method for fluconazole revealed that 21.1% of the isolates were resistant.
CONCLUSION:
More than 20% of the unselected women were colonized with Candida species. Hyperestrogenemia was associated with an increased vulvovaginal colonization by Candida. Surprisingly, 21% of the isolates was resistant to fluconazole, according to the National Committee for Clinical Laboratory Standards method.
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/12237629http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/40651
Citation
Bauters TG, Dhont MA, Temmerman MI, Nelis HJ.,Prevalence of vulvovaginal candidiasis and susceptibility to fluconazole in women,Am J Obstet Gynecol. 2002 Sep;187(3):569-74.Publisher
University of Nairobi, College of Health Sciences,
Collections
- Faculty of Health Sciences (FHS) [10378]