Bacterial vaginosis is associated with uterine cervical human papillomavirus infection: a meta-analysis.
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Date
2011Author
Gillet, E
Meys, JF
Verstraelen, H
Bosire, C
De Sutter, P
Temmerman, M
Broeck, DV
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Background:
Bacterial vaginosis (BV), an alteration of vaginal flora involving a decrease in Lactobacilli and
predominance of anaerobic bacteria, is among the most common cause of vaginal complaints for women of
childbearing age. It is well known that BV has an influence in acquisition of certain genital infections. However,
association between BV and cervical human papillomavirus (HPV) infection has been inconsistent among studies.
The objective of this meta-analysis of published studies is to clarify and summarize published literature on the
extent to which BV is associated with cervical HPV infection.
Methods:
Medline and Web of Science were systematically searched for eligible publications until December 2009.
Articles were selected based on inclusion and exclusion criteria. After testing heterogeneity of studies, meta-
analysis was performed using random effect model.
Results:
Twelve eligible studies were selected to review the association between BV and HPV, including a total of
6,372 women. The pooled prevalence of BV was 32%. The overall estimated odds ratio (OR) showed a positive
association between BV and cervical HPV infection (OR, 1.43; 95% confidence interval, 1.11-1.84).
Conclusion:
This meta-analysis of available literature resulted in a positive association between BV and uterine
cervical HPV infection
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/21223574http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/40672
Citation
BMC Infect Dis. 2011 Jan 11;11:10. doi: 10.1186/1471-2334-11-10.Collections
- Faculty of Health Sciences (FHS) [10377]