dc.contributor.author | Beerens, E | |
dc.contributor.author | Van, Renterghem L | |
dc.contributor.author | Praet, M | |
dc.contributor.author | Sturtewagen, Y | |
dc.contributor.author | Weyers, S | |
dc.contributor.author | Temmerman, M | |
dc.contributor.author | Depypere, H | |
dc.contributor.author | Claeys, P | |
dc.contributor.author | Cuvelier, CA | |
dc.date.accessioned | 2013-06-26T15:49:11Z | |
dc.date.available | 2013-06-26T15:49:11Z | |
dc.date.issued | 2005-08 | |
dc.identifier.citation | Cytopathology. 2005 Aug;16(4):199-205. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/16048506 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/40757 | |
dc.description.abstract | OBJECTIVES:
In this study, we focus on the prevalence and occurrence of different anogenital human papillomavirus (HPV) genotypes in a first abnormal cervical screening test, and correlate HPV genotyping with the cytological diagnosis on thin-layer liquid-based preparations in routine gynaecological screening.
METHODS:
Out of 780 abnormal smears, 513 tested positive for HPV. All 25 different HPV types were identified by Line Probe Assay.
RESULTS:
The prevalence of high-risk HPV types increased from 72% in atypical squamous cell of undetermined significance to 94.5% in high-grade intra-epithelial lesion (HSIL). Co-infection with multiple HPV types was predominantly found in HSIL (35.8%). In the HSIL group the most common HPV types were 16, 52, 51 and 31; type 18 was rarely present.
CONCLUSION:
The role of types 31, 51 and 52 should be considered in future studies on vaccine development. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi. | en |
dc.title | Human papillomavirus DNA detection in women with primary abnormal cytology of the cervix: prevalence and distribution of HPV genotypes. | en |
dc.type | Article | en |
local.publisher | College of Health Sciences | en |