Prevalence and types of coinfections in sleeping sickness patients in kenya (2000/2009).
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Date
2011Author
Kagira, JM
Maina, N
Njenga, J
Karanja, SM
Karori, SM
Ngotho, JM
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The occurrence of coinfections in human African trypanosomiasis (HAT) patients was investigated using a retrospective data of hospital records at the National Sleeping Sickness Referral Hospital in Alupe, Kenya. A total of 31 patients, 19 males and 12 females, were diagnosed with HAT between the years 2000 and 2009. The observed co-infections included malaria (100%), helminthosis (64.5%), typhoid (22.5%), urinary tract infections (16.1%), HIV (12.9%), and tuberculosis (3.2%). The species of helminthes observed included Ancylostoma duodenale (38.7%), Ascaris lumbricoides (45.7%), Strongyloides stercoralis (9.7%), and Taenia spp. (3.2%). The patients were also infected with Entamoeba spp. (32.3%) and Trichomonas hominis (22.6%) protozoan parasites. The main clinical signs observed at the point of admission included headache (74.2%), fever (48.4%), sleep disorders (45.2%), and general body pain (41.9%). The HAT patients were treated with suramin (early stage, 9/31) and melarsoprol (late stage, 22/31). In conclusion, the study has shown that HAT patients have multiple co-infections which may influence the disease pathogenesis and complicate management of HAT.
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/21915184http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/41284
Citation
J Trop Med. 2011;2011:248914. doi: 10.1155/2011/248914. Epub 2011 Sep 11Publisher
University of Nairobi Department of Tropical Infectious Diseases
Collections
- Faculty of Health Sciences (FHS) [10378]