Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders
View/ Open
Date
2005-06Author
Tinneberg, Hans Rudolf
Roberts, Timothy K
Gruessner, Susanne E M
Omwandho, Charles O A
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Recurrent pregnancy loss has been associated with autoimmune responses to membrane phospholipids and alloimmune reactions against paternally derived molecules on the trophoblast. The problem is psychologically and economically stressful as it undermines the capacity of some couples to reproduce and participate effectively in the day-to-day economic activities. This article reviews the adoption of intravenous immunoglobulin as a form of therapy for the clinical management of recurrent pregnancy loss and of selected autoimmune disorders. Side effects, contraindications and safety of use are discussed.
Citation
Clinical Chemistry and Laboratory Medicine. Volume 42, Issue 4, Pages 359–370Publisher
Department of Biochemistry
Collections
- Faculty of Health Sciences (FHS) [10377]