| dc.contributor.author | Yenesew Abiy. | |
| dc.contributor.author | Induli Martha. | |
| dc.contributor.author | Derese Solomon. | |
| dc.contributor.author | Midiwo Jacob O. | |
| dc.contributor.author | Heydenreich Matthias. | |
| dc.contributor.author | Peter Martin G | |
| dc.contributor.author | Akala Hoseah. | |
| dc.contributor.author | Wangui Julia. | |
| dc.contributor.author | Liyala Pamela. | |
| dc.contributor.author | Waters Norman C. | |
| dc.date.accessioned | 2013-07-03T09:20:56Z | |
| dc.date.available | 2013-07-03T09:20:56Z | |
| dc.date.issued | 2004 | |
| dc.identifier.citation | Abiy Yenesew, Martha Induli, Solomon Derese et al (2004). Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica. Phytochemistry Volume 65, Issue 22, November 2004, Pages 3029–3032 | en |
| dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S003194220400442X | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/44548 | |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/15504437 | |
| dc.description.abstract | The ethyl acetate extract of the stem bark of Erythrina abyssinica showed anti-plasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC50 values of 7.9 ± 1.1 and 5.3 ± 0.7 μg/ml, respectively. From this extract, a new chalcone, 2′,3,4,4′-tetrahydroxy-5-prenylchalcone (trivial name 5-prenylbutein) and a new flavanone, 4′,7-dihydroxy-3′-methoxy-5′-prenylflavanone (trivial name, 5-deoxyabyssinin II) along with known flavonoids have been isolated as the anti-plasmodial principles. The structures were determined on the basis of spectroscopic evidence. | en |
| dc.language.iso | en | en |
| dc.title | Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica | en |
| dc.type | Article | en |
| local.publisher | Department of Chemistry, University of Nairobi | en |
| local.publisher | Institut für Chemie, Universität Potsdam, Germany | en |
| local.publisher | United States Army Medical Research Unit-Kenya, USA | en |
