| dc.contributor.author | Irshad, M | |
| dc.contributor.author | Gandhi, BM | |
| dc.contributor.author | Acharya, KS | |
| dc.contributor.author | Joshi, YK | |
| dc.contributor.author | Tandon, BN | |
| dc.date.accessioned | 2013-07-05T07:16:02Z | |
| dc.date.available | 2013-07-05T07:16:02Z | |
| dc.date.issued | 1990 | |
| dc.identifier.citation | KIRTDA, DRACHARYAS. 1990. Irshad M, Gandhi BM, Acharya SK, Joshi YK, Tandon BN.Significance of anti-pre-S antibodies in patients with fulminant hepatic failure.Gastroenterol Jpn. 1990 Aug;25(4):499-502.. | en |
| dc.identifier.uri | http://profiles.uonbi.ac.ke/sacharya/publications/irshad-m-gandhi-bm-acharya-sk-joshi-yk-tandon-bnsignificance-anti-pre-s-antibo | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/45642 | |
| dc.description.abstract | Anti-pre-S antibody was tested in 38 sera from patients with fulminant hepatitis (positive for HBsAg and/or IgM anti-HBc) using a specific solid phase enzyme linked immunosorbent assay (ELISA). Anti-pre-S activity was detected in 50 percent sera samples positive for HBsAg but negative for IgM anti-HBc. There were 12.5% sera positive for both HBsAg as well as IgM anti-HBc and 75% sera negative for HBsAg but positive for IgM anti-HBc. The prevalence of HBV-specific DNA-polymerase activity was high in all the three groups whereas anti-HBs positivity was low. Anti-pre-S activity was observed both in the presence as well as in the absence of DNA-polymerase activity. High-anti-pre-S level in fulminant hepatitis B patients was assumed to be implicated in the fast clearance of HBsAg from circulation. | en |
| dc.language.iso | en | en |
| dc.title | Significance of anti-pre-S antibodies in patients with fulminant hepatic failure | en |
| dc.type | Article | en |
| local.publisher | Department of Medicine, College of Health Sciences, University of Nairobi | en |
