Relation between HBsAg binding with polymerized human serum albumin and HBV replication.
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Date
1987Author
Irshad, M
Gandhi, BM
Acharya, KS
Tandon, BN
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The binding between hepatitis B surface antigen (HBsAg) and polymerized human serum albumin (poly-HSA) was studied in HBsAg-negative (25) and HBsAg-positive (92) sera by a sensitive enzyme-linked immunosorbent assay technique, and a correlation of binding activity was made with HBe-markers and hepatitis B virus-specific DNA polymerase. The binding could be detected only in HBsAg-positive sera and was found to be independent of the presence of HBe-markers and DNA polymerase activity. Further, binding was noted in significantly higher proportions of sera samples from the patient group compared with the healthy carrier group (p less than 0.01).
URI
http://profiles.uonbi.ac.ke/sacharya/publications/irshad-m-gandhi-bm-acharya-sk-tandon-bnrelation-between-hbsag-binding-polymerihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/46817
Citation
KIRTDA, DRACHARYAS. 1987. Irshad M, Gandhi BM, Acharya SK, Tandon BN.Relation between HBsAg binding with polymerized human serum albumin and HBV replication.Intervirology. 1987;27(2):91-4..Publisher
Department of Medicine, College of Health Sciences, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10378]