Entamoeba histolytica: elevated nitroblue tetrazolium reduction activity in polymorphs during amoebic liver abscess.
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Date
1987Author
Gandhi, BM
Acharya, KS
Irshad, M
Gupta, H
Chawla, TC
Tandon, BN
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Peripheral blood polymorphonuclear leucocytes (PMN) from patients with invasive amoebiasis, i.e. amoebic liver abscess (ALA) and acute amoebic dysentery, showed marked elevation of nitroblue tetrazolium dye (NBT) reduction. This dramatic change was not observed in PMN from patients with non-invasive amoebiasis, i.e. non-suppurative hepatic amoebiasis, or in asymptomatic Entamoeba histolytica cyst passers. A small number (12%) of patients with viral hepatitis displayed increased NBT reduction. 10 to 12 days after recovery following treatment, the majority (75%) of ALA patients failed to show increased NBT reduction. Our results suggest that the PMN-NBT reduction test could be useful as an aid to the diagnosis of ALA.
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http://profiles.uonbi.ac.ke/sacharya/publications/gandhi-bm-acharya-sk-irshad-m-gupta-h-chawla-tc-tandon-bnentamoeba-histolyticahttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/46823
Citation
KIRTDA, DRACHARYAS. 1987. Gandhi BM, Acharya SK, Irshad M, Gupta H, Chawla TC, Tandon BN.Entamoeba histolytica: elevated nitroblue tetrazolium reduction activity in polymorphs during amoebic liver abscess.Trans R Soc Trop Med Hyg. 1987;81(2):283-5.Publisher
Department of Medicine, College of Health Sciences, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10387]