dc.contributor.author | Gilks, Charles F | |
dc.contributor.author | Brindle, Richard J | |
dc.contributor.author | Mwachari, Christine | |
dc.contributor.author | Batchelor, Barry | |
dc.contributor.author | Bwayo, JJ | |
dc.contributor.author | Kimari, Joseph | |
dc.contributor.author | Arbeit, Robert D | |
dc.contributor.author | von Reyn, C. Fordham | |
dc.date.accessioned | 2013-07-27T09:26:57Z | |
dc.date.available | 2013-07-27T09:26:57Z | |
dc.date.issued | 1995 | |
dc.identifier.citation | Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology February 1995 - Volume 8 - Issue 2 | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/7834402 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/51725 | |
dc.description.abstract | Summary: Previous studies from Africa have been unable to identify disseminated Mycobacterium avium complex (MAC) infection in patients with advanced human immunodeficiency virus (HIV) infection. We performed myco-bacterial blood cultures and CD4 counts on 48 symptomatic adults with advanced HIV infection admitted to the hospital in Nairobi, Kenya over 4 weeks in 1992. Fourteen patients had mycobacteremia; these patients had significantly lower CD4 counts than the patients with negative cultures (14/mm3 vs. 85/mm3;p < 0.01). Three patients (6%) were bacteremic with M. avium (mean CD4 count, 10/mm3) and 11 (23%) were bacteremic with Mycobacterium tuberculosis complex (MTB) (mean CD4 count, 15/mm3). Thus, M. avium bacteremia was detected significantly less frequently in the study population than MTB bacteremia (p = 0.04). The minimum rate for HIV-associated disseminated M. avium infection in patients admitted to the hospital in Nairobi was estimated to be approximately 1%. Patients with mycobacteremia died or were discharged home sick before the diagnosis was made. Disseminated M. avium does occur in adults with advanced HIV infection in sub-Saharan Africa, but is less common than disseminated MTB | en |
dc.language.iso | en | en |
dc.title | Disseminated Mycobacterium avium Infection Among HIV-Infected Patients in Kenya | en |
dc.type | Article | en |
local.publisher | Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya; | en |