Synthesis and in vivo antihyperglycemic activity of nature-mimicking furanyl-2-pyranones in STZ-S model.

dc.contributor.author	Singh, FV
dc.contributor.author	Chaurasia, S
dc.contributor.author	Joshi, MD
dc.contributor.author	Srivastava, AK
dc.contributor.author	Goel, A
dc.date.accessioned	2013-07-31T13:44:49Z
dc.date.available	2013-07-31T13:44:49Z
dc.date.issued	2007
dc.identifier.citation	Bioorg Med Chem Lett. 2007 May 1;17(9):2425-9. Epub 2007 Feb 17.	en
dc.identifier.uri	http://www.ncbi.nlm.nih.gov/pubmed/17336063
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/53091
dc.description.abstract	Various nature-mimicking pyranones such as 6-(2,5-dimethylfuran-3-yl)-pyran-2-one and 6-(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo antihyperglycemic activity in sucrose-loaded streptozotocin-induced diabetic rat model. Five of the test compounds showed significant lowering of plasma glucose level in STZ-S model.	en
dc.language.iso	en	en
dc.publisher	University of Nairobi	en
dc.title	Synthesis and in vivo antihyperglycemic activity of nature-mimicking furanyl-2-pyranones in STZ-S model.	en
dc.type	Article	en
local.publisher	Faculty of medicine	en