| dc.contributor.author | Nyong'o, Aggrey O | |
| dc.contributor.author | Manop, Huntrakoon | |
| dc.contributor.author | Parsa, Cyrus | |
| dc.contributor.author | Raja, Abdul | |
| dc.date.accessioned | 2013-08-02T06:21:17Z | |
| dc.date.available | 2013-08-02T06:21:17Z | |
| dc.date.issued | 1986 | |
| dc.identifier.citation | 1986, Vol. 18, No. 4 , Pages 473-477 | en |
| dc.identifier.uri | http://informahealthcare.com/doi/abs/10.3109/00313028609087572 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/53739 | |
| dc.description.abstract | A case of neurosarcomatous nodal metastasis of superficial spreading malignant melanoma, without primary site desmoplasia or sarcomatous changes, is reported. Of particular interest regarding the metastasis are: the ultrastructural demonstration of numerous cytoplasmic microtubules, absence of premeianosomes, intense immunohistochemical reaction with S-100 protein antibody, and the presence, at the light microscopic level, of extranodal fibrosis. The primary lesion shows a preexisting benign nevus and features suggestive of lamellar fibroplasia. The origin and histogenesis of melanocytic desmoplasia, in the context of a neural crest progenitor cell, and of lamellar fibroplasia, are discussed. | en |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi | en |
| dc.subject | Superficial spreading malignant melanoma, desmoplastic malignant melanoma, S-100 protein, neurosarcomatous metastasis, neural crest, lamellar fibroplasia, intracisternal tubules Read More: http://informahealthcare.com/doi/abs/10.3109/00313028609087572 | en |
| dc.title | Superficial spreading malignant melanoma with neurosarcomatous metastasis | en |
| dc.type | Article | en |
| local.publisher | Department of Human Pathology | en |
