Strategies to Manage Retinoplastoma in Developing Countries
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Date
2011-03Author
Chantada, Guillermo L
Qaddoumi, Ibrahim
Canturk, Serife
Khetan, Vikas
Ma, Zhigui
Kimani, Kahaki
Yeniad, Baris
Sultan, Iyad
Sitorus, Rita S
Tacyildiz, Nurdan
Abramson, David H
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Survival of retinoblastoma is >90% in developed countries but there are significant differences with developing countries in stage at presentation, available treatment options, family compliance, and survival. In low-income countries (LICs), children present with advanced disease, and the reasons are socioeconomic and cultural. In middle-income countries (MICs), survival rates are better (>70%), but there is a high prevalence of microscopically disseminated extraocular disease. Programs for eye preservation have been developed, but toxicity-related mortality is higher. Although effective treatment of microscopically extraocular disease improved the outcome, worldwide survival will be increased only by earlier diagnosis and better treatment adherence.
URI
http://onlinelibrary.wiley.com/doi/10.1002/pbc.22843/fullhttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/54388
Citation
Pediatric Blood & Cancer Volume 56, Issue 3, pages 341–348, March 2011Publisher
University of Nairobi Faculty of medicine
Collections
- Faculty of Health Sciences (FHS) [10377]