Schistosomiasis among young children in Usoma, Kenya
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Date
2011-05Author
Verani, JR
Abudho, B
Montgomery, SP
Mwinzi, PN
Shane, HL
Butler, SE
Karanja, DM
Secor, WE
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Although schistosomiasis burden is greatest among school-age children (SAC) (6-15 years of age), infection among preschool-age children (PSAC) (1-5 years), may be underestimated in endemic areas. We conducted a cross-sectional study evaluating Schistosoma mansoni infection among children 1-15 years of age in a highly endemic community in Kenya. Diagnostic tests included stool exam (Kato/Katz technique), serum testing for schistosome-specific antibodies, and urine testing for circulating cathodic antigen (CCA). Overall, 268 SAC and 216 PSAC were enrolled; prevalence increased with age, with 14% of 1 year olds and more than 90% of children > 10 years of age infected. Stool exam was more sensitive among SAC than PSAC, but performance was similar after adjusting for infection intensity (based on CCA). Schistosomiasis poses a threat to PSAC in endemic areas, and stool exam may underestimate the prevalence of infection. Control programs in such areas should consider PSAC in addition to SAC
URI
http://www.ncbi.nlm.nih.gov/pubmed/21540390http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/57631
Citation
Verani jr, Adudho B, Montgomery SP, Mwinzi PN, Shane HL, Butler SE, Karanja DM, Secor WE.Schistosomiasis among young children in Usoma, Kenya. Am J Trop Med Hyg. 2011 May; 84 (5): 787-91Publisher
University of Nairobi College of Health Science
Collections
- Faculty of Health Sciences (FHS) [10378]