Prevalence of anti-thyroid antibodies in patients with primary thyroid disorders.
View/ Open
Date
2008-09Author
Kuria, JG
Amayo, A.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
OBJECTIVE:
To determine prevalence of thyroid antimicrosomal and antithyroglobulin antibodies among patients with primary thyroid disorders.
DESIGN:
Descriptive cross-sectional study.
SETTING:
Kenyatta National Hospital, July 2003 to August 2004.
RESULTS:
Antimicrosomal antibodies (anti-TPOAbs) were detected in 51.4% of all the patients while 36.1% tested positive for the antithyroglobulin antibodies (anti- TgAbs). Among the hyperthyroid patients, anti-TPOAbs and anti-TgAbs were in 50.8% and 33% respectively while 53.3% and 46.7% of the hypothyroid patients tested positive for anti-TPOAbs and anti-TgAbs respectively. Most of the patients who showed positivity for anti-TgAbs (88.5%) also tested positive for anti-TPOAbs.
CONCLUSION:
More than half of the patients with primary thyroid disorders show presence of autoimmune thyroid markers, with anti TPO antibodies being more prevalent.
URI
http://www.ncbi.nlm.nih.gov/pubmed/19537420http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/57839
Citation
East Afr Med J. 2008 Sep;85(9):459-62.Publisher
University of Nairobi school of public health
Collections
- Faculty of Health Sciences (FHS) [10378]