Evaluation of corneal biomechanical properties following penetrating keratoplasty using ocular response analyzer.
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Date
2013Author
Murugesan, V
Bypareddy, R
Kumar, M
Tanuj, D
Anita, P
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Purpose: To evaluate corneal biomechanical properties in eyes that has undergone penetrating keratoplasty (PK). Materials and Methods: Retrospective observational study in a tertiary care centre. Data recorded included ocular response analyzer (ORA) values of normal and post-keratoplasty eyes [corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and cornea-compensated intraocular pressure (IOPcc)], corneal topography, and central corneal thickness (CCT). Wilcoxon signed rank test was used to analyze the difference in ORA parameter between post-PK eyes and normal eyes. Correlation between parameters was evaluated with Spearman's rho correlation. Results: The ORA study of 100 eyes of 50 normal subjects and 54 post-keratoplasty eyes of 51 patients showed CH of 8.340 ± 1.85 and 9.923 ± 1.558, CRF of 8.846 ± 2.39 and 9.577 ± 1.631 in post-PK eyes and normal eyes, respectively. CH and CRF did not correlate with post-keratoplasty astigmatism (P = 0.311 and 0.276, respectively) while a significant correlation was observed with IOPg (P = 0.004) and IOPcc (P < 0.001). Conclusion: Biomechanical profiles were significantly decreased in post-keratoplasty eyes with significant correlation with higher IOP as compared with that in normal eyes.
URI
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/58003http://www.ncbi.nlm.nih.gov/pubmed/24145556
Publisher
University of Nairobi College of Health Science
Collections
- Faculty of Health Sciences (FHS) [10378]