dc.contributor.author | Soh, J | |
dc.contributor.author | Rositch, AF | |
dc.contributor.author | Koutsky, L | |
dc.contributor.author | Guthrie, BL | |
dc.contributor.author | Choi, RY | |
dc.contributor.author | Bosire, RK | |
dc.contributor.author | Gatuguta, A | |
dc.contributor.author | Smith, JS | |
dc.contributor.author | Kiarie, J | |
dc.contributor.author | Lohman-Payne, B | |
dc.contributor.author | Farquhar, C. | |
dc.date.accessioned | 2013-12-04T07:10:02Z | |
dc.date.available | 2013-12-04T07:10:02Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Int J STD AIDS. 2013 Oct 7. [Epub ahead of print] | en_US |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/24047885 | |
dc.identifier.uri | http://hdl.handle.net/11295/61678 | |
dc.description.abstract | Individual and sexual partner characteristics may increase the risk of abnormal cervical cytology among women in human immunodeficiency virus (HIV)-discordant relationships. Papanicolaou smears were obtained in a prospective cohort of Kenyan HIV-discordant couples. Of 441 women, 283 (64%) were HIV-infected and 158 (36%) were HIV-uninfected with HIV-infected partners. Overall, 79 (18%) had low-grade and 25 (6%) high-grade cervical abnormalities. Male herpes simplex virus type 2 (HSV-2) seropositivity and lower couple socioeconomic status were associated with cervical abnormalities (p < 0.05). HIV-uninfected women with HIV-infected male sex partners (CD4 > 350 cells/µL) had the lowest prevalence of high-grade cervical lesions. HIV-infected women (CD4 > 350 cells/µL) and HIV-uninfected women with HIV-infected partners (CD4 ≤ 350 cells/µL) were at similar intermediate risk (p > 0.05), and HIV-infected women (CD4 ≤ 350 cells/µL) had significantly higher risk of high-grade cervical abnormalities (p = 0.05). Women in HIV-discordant relationships have high rates of cervical lesions and this may be influenced by couple-level factors, including HIV status and CD4 count of the infected partner. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.subject | Cancer, HIV, cervical, cytology, discordant couples | en_US |
dc.title | Individual and partner risk factors associated with abnormal cervical cytology among women in HIV-discordant relationships. | en_US |
dc.type | Article | en_US |