dc.contributor.author | Albert, Randrianjafy | |
dc.contributor.author | Tachibana, Yoko | |
dc.contributor.author | Nishiyama, Yumi | |
dc.contributor.author | Mathenge, Simon G | |
dc.contributor.author | Kato, Atsushi | |
dc.contributor.author | Miura, Toshihiro | |
dc.contributor.author | Ohnishi, Yasuhiro | |
dc.date.accessioned | 2014-04-02T07:33:14Z | |
dc.date.available | 2014-04-02T07:33:14Z | |
dc.date.issued | 1999 | |
dc.identifier.citation | Atsushi Kato et al, Am. J. Chin. Med. 27, 365 (1999) | en_US |
dc.identifier.uri | http://www.worldscientific.com/doi/abs/10.1142/S0192415X99000410 | |
dc.identifier.uri | http://hdl.handle.net/11295/65726 | |
dc.description.abstract | Intraperitoneal administration of the methanol extract of Embelia schiperi (ES) to normal mice caused a significant decrease in blood glucose (p < 0.01) and a significant increase in triglycerides 4 hours after administration at 100 mg/kg (p < 0.01). The toluene fraction of Embelia keniensis methanol extract (TS) showed hypoglycemic and lipid lowering activity 7 hours after intraperitoneal administration at 100 mg/kg. In addition, TS (100 mg/kg) administration significantly decreased blood glucose in epinephrine-induced hyperglycemic mice (p < 0.01). Moreover, ES tended to increase while TS tended to decrease the blood triglycerides in epinephrine-induced hyperglycemic mice. On the other hand, no changes in blood cholesterol were observed after the administration of ES or TS in normal and epinephrine-induced hyperglycemic mice. We found that two species from Embelia, ES and TS, have different activities on blood glucose and triglycerides in normal and epinephrine-induced hyperglycemic mice. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.title | A Comparative Study of Embelia Schiperi and Embelia Keniensis on Blood Glucose and Triglycerides in Normal and Epinephrine- Induced Hyperglycemic Mice | en_US |
dc.type | Article | en_US |