| dc.contributor.author | Baeten, Jared M | |
| dc.contributor.author | Chohan, Bhavna | |
| dc.contributor.author | Lavreys, Ludo | |
| dc.contributor.author | Chohan, Vrasha | |
| dc.contributor.author | McClelland, R Scott | |
| dc.contributor.author | Certain, Laura | |
| dc.contributor.author | Mandaliya, Kishorchandra | |
| dc.contributor.author | Jaoko, Walter | |
| dc.contributor.author | Julie, Overbaugh | |
| dc.date.accessioned | 2014-08-15T06:38:46Z | |
| dc.date.available | 2014-08-15T06:38:46Z | |
| dc.date.issued | 2007 | |
| dc.identifier.citation | J Infect Dis. (2007) 195 (8): 1177-1180. | en_US |
| dc.identifier.uri | http://jid.oxfordjournals.org/content/195/8/1177.short | |
| dc.identifier.uri | http://hdl.handle.net/11295/73771 | |
| dc.description.abstract | We investigated the effect of human immunodeficiency virus type 1 (HIV-1) subtype on disease progression among 145 Kenyan women followed from the time of HIV-1 acquisition. Compared with those infected with subtype A, women infected with subtype D had higher mortality (hazard ratio, 2.3 [95% confidence interval, 1.0–5.6]) and a faster rate of CD4 cell count decline (P = .003). The mortality risk persisted after adjustment for plasma HIV-1 load. There were no differences in plasma viral load by HIV-1 subtype during follow-up. HIV-1 subtype D infection is associated with a >2-fold higher risk of death than subtype A infection, in spite of similar plasma HIV-1 loads. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | University of Nairobi | en_US |
| dc.title | HIV-1 Subtype D Infection Is Associated with Faster Disease Progression than Subtype A in Spite of Similar Plasma HIV-1 Loads | en_US |
| dc.type | Article | en_US |
| dc.type.material | en | en_US |
