Browsing Journal Articles by Title
Now showing items 5886-5905 of 29885
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CYP2B6 genetic polymorphism and its impact on efavirenz plasma levels in HIV/AIDS out-patients of African origin
(Department of Pharmacology and Pharmacognosy, 2008)The non-nucleoside reverse transcriptase inhibitor, efavirenz is metabolized primarily by the polymorphic cytochrome P450 2B6 (CYP2B6), and high plasma concentrations of the drug are associated with a single nucleotide ... -
Cytochrome oxidase 1 gene and its application in wildlife forensics in Kenya
(University of Nairobi, 2013)In African countries in general and Kenya specifically, wildlife crimes are leading an increasing number of species to the brink of extinction. This is partly because the perpetrators of these crimes once caught don't get ... -
Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study
(2015-04-15)Abstract Background Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African ... -
Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study
(University of Nairobi, 2015)Background: Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African populations, but data on their influence on plasma ... -
Cytochrome P450 3A mRNA expression along goat and rat gastrointestinal tracts
(Department of Public Health, Pharmacology and Toxicology, 2012)The cytochrome P450 (CYP) 3A family is involved in the elimination processes of almost 50% of commonly used drugs. CYP3A mRNA expressions in goat and rat gastrointestinal tracts in comparison to the liver were investigated ... -
Cytogenetic effects of the food preservatives — Sodium benzoate and sodium sulphite on Vicia faba root meristems
(1982-11)Sodium sulphite and sodium benzoate induce in Vicia faba root meristems: (1) dose-dependent reduction in mitotic figures, (2) intact and severed anaphase bridges, (3) premature chromosome condensation heading to pycnofic ... -
Cytogenetics of a new cytotype of African Mus (subgenus Nannomys) minutoides (Rodentia, Muridae) from Kenya: C- and G- banding and distribution of (TTAGGG)n telomeric sequences
(College of Biological and Physical Sciences, University of Nairobi, 2006) -
Cytokine and chemokine expression profiles in response to Mycobacterium tuberculosis stimulation are altered in HIV-infected compared to HIV-uninfected subjects with active tuberculosis.
(University of Nairobi, 2015-05-22)Mycobacterium tuberculosis (Mtb) infects nearly 2 million people annually and is the most common cause of death in HIV-infected individuals. Tuberculosis (TB) diagnostics cater to HIV-uninfected individuals in non-endemic ... -
Cytokine Expression and Hypertension Comorbidity in HIV/AIDS Patients at Kenyatta National Hospital HIV Care Centre, Nairobi, Kenya
(University of Nairobi, 2018)Chronic inflammation in HIV disease is sustained by immune reconstitution that results from use of combination therapy by patients and manifested by increased expression of inflammatory cytokines. Chronic inflammation in ... -
Cytokines and the malnutrition of chronic renal failure
(University of NairobiSchool of medicine,University of Nairobi, 1997)Malnutrition in uremic patients remains one of the major causes of morbidity and mortality. Its mediators remain largely unknown. Uremia is characterized by changes in circulating levels of catabolic cytokines and anabolic ... -
Cytokinin-to-gibberellin ratio regulates water status, ethylene evolution and senescence in lisianthus flowers via novel signaling pathway
(University of Nairobi, 2013)No abstract available -
Cytologic findings in adult patients presenting with haematuria in urology clinic at Kenyatta National Hospital.
(University of Nairobi, 2014)Haematuria is a common rinding in patients presenting with urologic problems. Therefore, the aim of this study was to describing the cytologic findings in patients presenting with haematuria in the urology clinic at ... -
Cytological evaluation of breast lesions in symptomatic patients presenting to Kenyatta National Hospital, Kenya: a retrospective study
(University of Nairobi, 2015)Background: Palpable breast lump, breast pain, and nipple discharge are common symptoms of breast disease. Breast cytology (fine-needle aspiration, nipple discharge smear, and touch preparation) accurately identifies ... -
Cytomorphological patterns of breast lesions among women with palpable breast lumps attending select teaching and referral hospitals in Kenya: a descriptive cross-sectional study
(University of Nairobi, 2023)Introduction: breast lumps account for a greater number of lesions in women attending surgical clinics in the developing world. Breast cancer which mostly presents as a breast lump is the leading cancer in Kenya, with an ... -
Cytomorphological Patterns of Palpable Breast Lesions Diagnosed in Selected Teaching and Referral Hospitals in Kenya: A Prospective Study
(Oxford University Press, 2019-09)To study the patterns of breast lesions among women with palpable breast lumps presenting to fine-needle aspiration clinics. Methods This study involved 768 women aged 16 to 97 years who presented with palpable breast ... -
Cytopenia among CML Patients on Imatinib in Kenya: Types, Grades, and Time Course.
(University of Nairobi, 2020)Background: Imatinib mesylate is the gold standard for the treatment of all phases of Philadelphia-positive chronic myeloid leukemia. Patients on imatinib treatment may develop cytopenia due to drug toxicity. This study ... -
Cytotoxic Actions Of Dendroaspis Venoms In Primary Cultures Of Rat Hepatocytes.
(University of NairobiDepartment of Medical Physiology, 1987)Abstract Not Available -
Cytotoxic activity of Ajuga remota
(University of NairobiSchool of medicine, 2002) -
Cytotoxic activity of medicinal plants of the Kakamega County (Kenya) against drug-sensitive and multidrug-resistant cancer cells.
(University of Nairobi, 2018)ETHNOPHARMACOLOGICAL RELEVANCE: The geographical location of Kakamega County proximal to the Kakamega Rain Forest in Kenya and its rich flora represents an interesting resource of traditional medicinal plants. The ...