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Treatment of hepatitis C virus infection in patients of northern India
(2004)
BACKGROUND AND AIM: The purpose of the present study was to evaluate the therapeutic response of north Indian patients with chronic hepatitis C (CH-C) to two different treatment regimens of interferon and ribavirin. METHODS: ...
Vitamin E-based therapy is effective in ameliorating transaminasemia in nonalcoholic fatty liver disease
(2005)
BACKGROUND: Comparative trials of ursodeoxycholic acid (UDCA), vitamin E and weight management programs among patients with nonalcoholic fatty liver disease (NAFLD) are lacking. AIM: To find an effective single agent or ...
Vaccination for hepatitis A virus is not required for patients with chronic liver disease in India
(2002)
BACKGROUND: Hepatitis A virus (HAV) vaccination is recommended worldwide for patients with chronic liver disease to prevent decompensation due to superinfection with HAV. India being endemic for HAV, the prevalence of ...
Occult hepatitis B virus infection in chronic liver disease: full-length genome and analysis of mutant surface promoter
(2004)
BACKGROUND AND AIMS: Genome sequence of hepatitis B virus (HBV) from occult chronic infection is scarce. Fifty-six (9.4%) of 591 patients seronegative for hepatitis B surface antigen (HBsAg) with chronic liver disease were ...
Role of polymerase chain reaction and liver biopsy in the evaluation of patients with asymptomatic transaminitis: implications in diagnostic approach
(2004)
BACKGROUND AND AIM: Detection of an asymptomatic rise in the hepatic aminotransferase (ARHA) value has become a distinct and frequent clinical problem. We evaluated a three-step diagnostic algorithm in such patients for ...
Clinical relevance of HBV DNA load in patients with chronic hepatitis B infection.
(2008)
BACKGROUND: Hepatitis B virus (HBV) DNA detection and quantification are now playing an increasing role in the assessment of disease activity and response to therapy. However, viraemia levels which define various stages ...
A 20-year single-center experience with acute liver failure during pregnancy: Is the prognosis really worse?
(2008)
Pregnant patients with acute liver failure (ALF) are believed to have a worse outcome than nonpregnant women and men with ALF. However objective data supporting this supposition are scant. Therefore, the current study ...
Non-alcoholic fatty liver disease may not be a severe disease at presentation among Asian Indians.
(2006)
AIM: To evaluate the clinical and biochemical profile of patients with non alcoholic fatty liver disease (NAFLD) and to assess their histological severity at presentation. METHODS: Consecutive patients presenting to the ...
Hepatitis E virus: epidemiology, diagnosis, pathology and prevention.
(2006)
HEV, a positive stranded RNA virus, is responsible for most of the epidemics of hepatitis in the developing world and is transmitted through contaminated water. It is the major aetiological agent for acute hepatitis and ...
Vaccination against hepatitis A virus may not be required for schoolchildren in northern India
(2002)
OBJECTIVES: To evaluate the current seroprevalence of antibodies against hepatitis A virus (HAV) in a sample of schoolchildren above 10 years of age and to determine the prevalence of HAV-induced hepatitis in adults at a ...