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Now showing items 211-220 of 271
Constituents of Croton Megalocarpus With Potential Anti-hiv Activity
(University of Nairobi, 2022)
Reported herein is an anti-HIV monochlorinated compound, 1β-acetoxy-3β-chloro-5α,6α-dihydroxycrotocascarin L (1), of the rare crotofolane diterpenoid class. Compound 1, a suspected artifact of extraction, along with the ...
A remarkable rodent: Regeneration and reproduction in spiny mice (Acomys)
(University of Nairobi, 2022-02)
Although certain organisms are chosen and employed to better understand a specific problem in biology (so-called model organisms), sometimes an animal model reveals its' biomedical importance by happenstance. In many ways, ...
Psychological Experiences of Caregivers of Adolescents Diagnosed With Substance Use Disorder Attending a Youth Centre in a Low-resource Setting
(University of Nairobi, 2022)
Caregivers, whether a biological parent, adoptive parent, or a relative such as a grandparent, of adolescent with substance use disorder (SUD) undergo immense psychological and social strains, as they have to deal with ...
Progress on the national action plan of Pakistan on antimicrobial resistance (AMR): a narrative review and the implications
(University of Nairobi, 2022-01)
Introduction: The emergence of antimicrobial resistance (AMR) is a threat to public health. In 2015, the World Health Organization (WHO) introduced a global action plan to tackle AMR in the World Health Assembly. Pakistan's ...
Pairwise Joint Modeling of Clustered and High-dimensional Outcomes With Covariate Missingness in Pediatric Pneumonia Care
(University of Nairobi, 2022)
Multiple outcomes reflecting different aspects of routine care are a common phenomenon in health care research. A common approach of handling such outcomes is multiple univariate analyses, an approach which does not allow ...
Potential pharmacologic interventions targeting TLR signaling in placental malaria
(University of Nairobi, 2022)
Complications from placental malaria cause poor pregnancy outcomes, including low birthweight, preterm delivery, and stillbirths. Many of these complications are driven by maternal innate proinflammatory responses to the ...
Comparison of Technical Efficiency and Technology Gaps Between Contracted and Non-contracted Vegetable Farmers in Western Kenya
(University of Nairobi, 2021)
Contract farming is an innovative institutional arrangement with potential benefits to the livelihood of value chain actors................................................................................................. ...
Longitudinal and cross-sectional validation of the WERCAP screen for assessing psychosis risk and conversion
(University of Nairobi, 2022-03)
Background: The Washington Early Recognition Center Affectivity and Psychosis (WERCAP) Screen was developed to assess risk for developing psychosis. Its validity has not been investigated in a large population-based study ...
Keloids: Does patients' sex influence the presentation and recurrence post-excision?
(University of Nairobi, 2022-01)
Keloid is a dermo-fibroproliferative disorder thought to result from abnormal proliferation of
fibroblasts. Few studies have been done to compare the clinical presentation and outcomes
of keloids based on gender. The ...
Rational use of antibiotics and covariates of clinical outcomes in patients admitted to intensive care units of a tertiary hospital in Kenya
(University of Nairobi, 2022-04)
Objectives: Rational use of antibiotics implies appropriate choice of an antibiotic administered at correct dose, frequency, and duration using the most suitable route of administration. Irrational antibiotics use is ...