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Regular use of depot medroxyprogesterone acetate causes thinning of the superficial lining and apical distribution of HIV target cells in the human ectocervix
(University of Nairobi, 2020)
Background: The hormonal contraceptive depot medroxyprogesterone acetate (DMPA) may be associated with an increased risk of acquiring human immunodeficiency virus (HIV). We hypothesize that DMPA use influences the ectocervical ...
Medroxyprogesterone Acetate Alters The Vaginal Microbiota And Microenvironment In Women And Increases Susceptibility To Hiv-1 In Humanized Mice
(Medroxyprogesterone Acetate Alters The Vaginal Microbiota And Microenvironment In Women And Increases Susceptibility To Hiv-1 In Humanized Mice, 2019)
The hormonal contraceptive medroxyprogesterone acetate (MPA) is associated with increased risk of human immunodeficiency virus (HIV), via incompletely understood mechanisms. Increased diversity in the vaginal microbiota ...
Increased Cervical CD4 + CCR5 + T Cells Among Kenyan Sex Working Women Using Depot Medroxyprogesterone Acetate
(University of Nairobi, 2019)
Depot medroxyprogesterone acetate (DMPA) is the most common hormonal contraceptive used by women in sub-
Saharan Africa, however, it has been epidemiologically associated with HIV infections. To assess whether DMPA
has ...
Prevalence, Incidence, and Distribution of Human Papillomavirus Types in Female Sex Workers in Kenya
(UoN, 2020)
Female sex workers (FSWs) have a notably high risk of acquiring human papillomavirus (HPV) infections. Relatively few studies address the type-specific prevalence and incidence of HPV among FSWs in sub-Saharan Africa. FSWs ...
Willingness to participate in future HIV vaccine trials among men who have sex with men and female sex workers living in Nairobi, Kenya
(University of Nairobi, 2020)
Objective
To evaluate factors associated with willingness to participate in future HIV vaccine trials among men who have sex with men and female sex workers living in Nairobi, Kenya.
Background
Working with ‘key ...
Characterization of occult hepatitis B in high-risk populations in Kenya
(University of Nairobi, 2020)
Occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the liver or serum in the absence of detectable HBV surface antigen (HBsAg). OBI poses a risk for the development of cirrhosis ...
The effects of COVID-19 on the health and socio-economic security of sex workers in Nairobi, Kenya: Emerging intersections with HIV
(University of Nairobi, 2020)
The COVID-19 pandemic, and its attendant responses, has led to massive health, social, and economic challenges on a global scale. While, so far, having a relatively low burden of COVID-19 infection, it is the response in ...
Association between Vaginal Bacterial Microbiota and Vaginal Yeast Colonization
(University of Nairobi, 2020)
Background: Vaginal yeast is frequently found with Lactobacillus-dominant microbiota. The relationship between vaginal yeast and other bacteria has not been well characterized.
Methods: These analyses utilized data from ...