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Hiv-specific T Cells: Strategies For Fighting A Moving Target.
(University of Nairobi, 2010)
HIV vaccine development faces many hurdles, including the failure of empirical approaches, an incomplete understanding of protective immunity, and the extreme genetic diversity of HIV-1. HIV is a moving target in at least ...
Substantial Intrapatient Differences In The Breadth And Specificity Of Hiv-specific Cd8+ T-cell Interferon-gamma And Proliferation Responses.
(University of Nairobi, 2008-10)
HIV vaccine design and evaluation require a better understanding of protective immune responses. HIV-specific CD8+ T-cell responses have been characterized extensively using interferon-gamma (IFN-gamma) enzyme-linked ...