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Inhibition of Proinflammatory Cytokine Release by Flavones and Flavanones from the Leaves of Dracaena steudneri Engl
(University of Nairobi, 2021-03)
The leaves of Dracaena steudneri yielded 6 new flavonoids-3,5,7-trihydroxy-6-methyl-3',4'-methylenedioxyflavone (1: ), 5,7-dihydroxy-3-methoxy-6-methyl-3',4'-methylenedioxyflavone (2: ), 3,5,7-trihydroxy-6-methoxy-3',4'- ...
Anti-inflammatory norhopanes from the root bark of Fagaropsis angolensis (Engl.) H.M.Gardner
(University of Nairobi, 2020)
Two new norhopane derivatives namely 3β,6β,22-trihydroxy-7β,11α-di[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (1) and 3β,6β,22-trihydroxy-7β-[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (2) together with two ...
Flavanols from Tetrapleura tetraptera with cytotoxic activities
(University of Nairobi, 2022-05)
Tetrapleura tetraptera is a medicinal plant used in East and West Africa to treat inflammation and related diseases. From the stem bark of the plant, three previously undescribed flavan-3-ol derivatives named (2R,3S)-3,3 ...
Mechanism of Action of Endophytic Fungi Hypocrea Lixii and Beauveria Bassiana in Phaseolus Vulgaris as Biopesticides Against Pea Leafminer and Fall Armyworm
(University of Nairobi, 2021-09)
Endophytic fungal isolates Hypocrea lixii F3ST1 and Beauveria bassiana G1LU3 were evalu-
ated for their potential to endophytically colonize and induce active compounds in Phaseolus vulgaris,
as a defense mechanism against ...
Antibacterial Secondary Metabolites From Vernonia Auriculifera Hiern (Asteraceae) Against Mdr Phenotypes
(University of Nairobi, 2022)
Purification of the aerial parts of Vernonia auriculifera Hiern
afforded steroids (1–2), flavonoids (3–5), and polyalcohol (6).
Their structures were determined using spectral evidences as well
as by comparison with ...
Conglomeratin: a New Antibacterial Flavonol Derivative From Macaranga Conglomerata Brenan (Euphorbiaceae)
(University of Nairobi, 2022)
A new prenylated kaempferol, conglomeratin (1), alongside 7 known
compounds including flavonoids (2 and 3), ellagic acid derivatives (4
and 5), triterpenoids (6 and 7), and a coumarin (8)were isolated from
the leaves ...
Cytotoxic Alkaloids From the Root of Zanthoxylum Paracanthum (Mildbr) Kokwaro
(University of Nairobi, 2022)
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four ...
Antiplasmodial and Antimicrobial Activities of Ent- Abietane Diterpenoids From the Roots of Suregada Zanzibariensis
(University of Nairobi, 2022)
The root extract ofSuregada zanzibariensisBaill. afforded six previ-ously describedent-abietane diterpenoids, namely 7-oxo-ent-abieta-5(6),8(14),13(15)-trien-16,12-olide (1), mangiolide (2),8,14b:11,12a-diepoxy ...
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
(University of Nairobi, 2022)
Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants
have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy
c ...
Laboratory and Field Performance of Metarhizium Anisopliae Isolate Icipe 41 for Sustainable Control of the Invasive Fall Armyworm Spodoptera Frugiperda (Lepidoptera: Noctuidae)
(University of Nairobi, 2022)
To overcome the negative impacts of invasive fall armyworm (FAW), this study assessed
the laboratory and field efficacy of aqueous and oil-based formulations of Metarhizium anisopliae
ICIPE 41 as an alternative source ...