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Inhibition of Proinflammatory Cytokine Release by Flavones and Flavanones from the Leaves of Dracaena steudneri Engl
(University of Nairobi, 2021-03)
The leaves of Dracaena steudneri yielded 6 new flavonoids-3,5,7-trihydroxy-6-methyl-3',4'-methylenedioxyflavone (1: ), 5,7-dihydroxy-3-methoxy-6-methyl-3',4'-methylenedioxyflavone (2: ), 3,5,7-trihydroxy-6-methoxy-3',4'- ...
Two new flavonoids from Dracaena usambarensis Engl.
(University of Nairobi, 2020)
Investigations of the root extract of Dracaena usambarensis Engl. for anticancer principles led to the characterization of one new homoisoflavonoid, (3S)-3,4ʹ,5,6-tetrahydroxy-7-methoxyhomoisoflavanone (1) and a new ...
Anti-inflammatory norhopanes from the root bark of Fagaropsis angolensis (Engl.) H.M.Gardner
(University of Nairobi, 2020)
Two new norhopane derivatives namely 3β,6β,22-trihydroxy-7β,11α-di[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (1) and 3β,6β,22-trihydroxy-7β-[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (2) together with two ...
Anti-inflammatory steroidal sapogenins and a conjugated chalcone-stilbene from Dracaena usambarensis Engl
(University of Nairobi, 2020)
Four new steroidal sapogenins, dracaenogenins CF (1-4), a new conjugated chalcone-stilbene, 3''-methoxycochinchinenene H (5) together with eight known compounds namely, (25S)-spirosta-1,4-dien-3-one (6), trans-resveratrol ...
Antibacterial Activities and Phytochemical Screening of Crude Extracts from Kenyan Macaranga Species Towards MDR Phenotypes Expressing Effux Pumps
(University of Nairobi, 2021)
Macaranga species are traditionally used for the
treatment and management of coughing, fungal infection, and wounds.
In this study, the phytochemical screening and antibacterial activities
of nine crude extracts from ...
Mechanism of Action of Endophytic Fungi Hypocrea Lixii and Beauveria Bassiana in Phaseolus Vulgaris as Biopesticides Against Pea Leafminer and Fall Armyworm
(University of Nairobi, 2021-09)
Endophytic fungal isolates Hypocrea lixii F3ST1 and Beauveria bassiana G1LU3 were evalu-
ated for their potential to endophytically colonize and induce active compounds in Phaseolus vulgaris,
as a defense mechanism against ...
Antibacterial Secondary Metabolites From Vernonia Auriculifera Hiern (Asteraceae) Against Mdr Phenotypes
(University of Nairobi, 2022)
Purification of the aerial parts of Vernonia auriculifera Hiern
afforded steroids (1–2), flavonoids (3–5), and polyalcohol (6).
Their structures were determined using spectral evidences as well
as by comparison with ...
Conglomeratin: a New Antibacterial Flavonol Derivative From Macaranga Conglomerata Brenan (Euphorbiaceae)
(University of Nairobi, 2022)
A new prenylated kaempferol, conglomeratin (1), alongside 7 known
compounds including flavonoids (2 and 3), ellagic acid derivatives (4
and 5), triterpenoids (6 and 7), and a coumarin (8)were isolated from
the leaves ...
Cytotoxic Alkaloids From the Root of Zanthoxylum Paracanthum (Mildbr) Kokwaro
(University of Nairobi, 2022)
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four ...
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
(University of Nairobi, 2022)
Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants
have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy
c ...