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Now showing items 161-170 of 191
Recent transmission of tuberculosis in a cohort of HIV-1-infected female sex workers in Nairobi, Kenya.
(University of Nairobi, 1997)
Abstract
OBJECTIVES:
To describe the epidemiological and clinical characteristics of HIV-related tuberculosis in a female cohort, and to investigate the relative importance of recently transmitted infection and ...
The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group.
(University of Nairobi, 1996)
Female sex workers in Nairobi were prospectively evaluated for risk factors of incident Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P=.007), gonococcal infection (P=.002), human ...
Systems biology-based approaches to understand HIV-exposed uninfected women.
(University of Nairobi, 2010-05)
Worldwide HIV infects women more frequently than men, and it is clear that not all exposed to HIV become infected. Several populations of HIV-exposed uninfected (EU) women have been identified, including discordant couples ...
Anti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells.
(University of Nairobi, 2012-12-27)
Elafin (E) and its precursor trappin-2 (Tr) are alarm antiproteases with antimicrobial and immunomodulatory activities. Tr and E (Tr/E) have been associated with HIV-1 resistance. We recently showed that Tr/E reduced IL-8 ...
Pyrosequencing of the chaperonin-60 universal target as a tool for determining microbial community composition.
(University of Nairobi, 2009-05)
We compared dideoxy sequencing of cloned chaperonin-60 universal target (cpn60 UT) amplicons to pyrosequencing of amplicons derived from vaginal microbial communities. In samples pooled from a number of individuals, the ...
Analysis of multimerization of the SARS coronavirus nucleocapsid protein
(University of Nairobi, 2004-04)
Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus. The genome of SARS Coronavirus (SARS-CoV) has recently been sequenced, ...
Effect of human immunodeficiency virus on local immunity in children with diarrhoea
(1995)
The purpose of this study was to determine the relationship between intestinal mucosal immunity and diarrhoea. Stools were tested for total IgA by radial immunodiffusion, cultured for bacteria and examined for ova/cysts ...
Risk factors for genital ulcerations in Kenyan sex workers. The role of human immunodeficiency virus type 1 infection.
(1997)
BACKGROUND AND OBJECTIVES: Genital ulcer disease (GUD) is a major risk factor for human immunodeficiency virus (HIV) transmission. Cross-sectional studies have suggested that HIV infection may itself predispose to genital ...