Search
Now showing items 11-15 of 15
Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial.
(University of Nairobi, 2013-08)
BACKGROUND:
Daily oral antiretroviral preexposure prophylaxis (PrEP) is a promising strategy for prevention of HIV-1 acquisition. Three clinical trials demonstrated PrEP efficacy; however, two PrEP trials among women ...
Pre-exposure prophylaxis for HIV-1 prevention does not diminish the pregnancy prevention effectiveness of hormonal contraception.
(University of Nairobi, 2014)
BACKGROUND:
For women at risk of HIV-1, effective contraception and effective HIV-1 prevention are global priorities.
METHODOLOGY:
In a clinical trial of pre-exposure prophylaxis (PrEP) for HIV-1 prevention in ...
HIV-1 subtype C is not associated with higher risk of heterosexual HIV-1 transmission: a multinational study among HIV-1 serodiscordant couples.
(University of Nairobi, 2014-01)
BACKGROUND:
HIV-1 subtype C has emerged as the most prevalent strain of HIV-1 worldwide, leading to speculation that subtype C may be more transmissible than other subtypes. We compared the risk of HIV-1 transmission ...
Reversibility of glomerular renal function decline in hiv-uninfected men and women discontinuing emtricitabine-tenofovir disoproxil fumarate pre-exposure prophylaxis.
(University of Nairobi, 2016)
BACKGROUND:
Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis (PrEP) use is associated with a small but statistically significant decline in estimated glomerular filtration rate (eGFR). We investigated the ...
Changes in Glomerular Kidney Function Among HIV-1-Uninfected Men and Women Receiving Emtricitabine-Tenofovir Disoproxil Fumarate Preexposure Prophylaxis: A Randomized Clinical Trial.
(University of Nairobi, 2014)
Importance:
Tenofovir disoproxil fumarate (TDF) use has been associated with declines in the estimated glomerular filtration rate (eGFR) when used as part of antiretroviral treatment by persons with human immunodeficiency ...