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Now showing items 21-29 of 29
Systemic Cytokine Levels Show Limited Correlation with Risk of HIV-1 Acquisition.
(University of Nairobi, 2014-01)
It has been hypothesized that immune activation and inflammation may increase HIV-1 susceptibility and that cytokines may be useful biomarkers for risk. Within a prospective cohort, we conducted a nested case-control ...
A Prospective Cohort Study of the Effect of Depot Medroxyprogesterone Acetate on Detection of Plasma and Cervical HIV-1 in Women Initiating and Continuing Antiretroviral Therapy
(University of Nairobi, 2014-05)
Depot medroxyprogesterone acetate (DMPA) use among HIV-1 infected women may increase transmission by increasing plasma and genital HIV-1 RNA shedding. We investigated associations between DMPA use and HIV-1 RNA in plasma ...
HIV-1 Superinfection Occurs Less Frequently Than Initial Infection in a Cohort of High-Risk Kenyan Women.
(2013)
HIV superinfection (reinfection) has been reported in several settings, but no study has been designed and powered to rigorously compare its incidence to that of initial infection. Determining whether HIV infection reduces ...
Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials
(2000)
Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...
Brief report: association between menopause and unprotected sex in high-risk HIV-positive women in Mombasa, Kenya20
(University of Nairobi, 2017)
OBJECTIVE:
Many HIV-positive women now live well beyond menopause. Postmenopausal women are no longer at risk for pregnancy, and some studies suggest that they may use condoms less often than premenopausal women. This ...
Alcohol use and associations with biological markers and self-reported indicators of unprotected sex in human immunodeficiency virus-positive female sex workers in Mombasa, Kenya.
(University of Nairobi, 2016)
BACKGROUND:
Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have ...
HIV-1 infection alters the retinol-binding protein:transthyretin ratio even in the absence of the acute phase response.
(University of Nairobi,, 2005)
he ratio of retinol-binding protein (RBP) to transthyretin (TTR) has been proposed as an indirect method with which to assess vitamin A status in the context of inflammation. Few studies have been conducted among adults, ...
HIV-1 acquisition and disease progression are associated with decreased high-risk sexual behaviour among Kenyan female sex workers.
(2006)
BACKGROUND:
Changes in sexual risk behaviour may occur following HIV-1 infection.
OBJECTIVE:
To test the hypothesis that HIV-1 seroconversion and disease progression are associated with changes in risk behaviours, ...