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HIV-1-specific enzyme-linked immunosorbent spot assay responses in HIV-1-exposed uninfected partners in discordant relationships compared to those in low-risk controls.
(2013)
A number of studies of highly exposed HIV-1-seronegative individuals (HESN) have found HIV-1-specific cellular responses. However, there is limited evidence that responses prevent infection or are linked to HIV-1 exposure. ...
A Prospective Cohort Study Comparing the Effect of Single-Dose 2 g Metronidazole on Trichomonas vaginalis Infection in HIV-Seropositive Versus HIV-Seronegative Women.
(University of Nairobi, 2013-06)
BACKGROUND:
This analysis compared the frequency of persistent Trichomonas vaginalis (TV) among HIV-seropositive and HIV-seronegative women.
METHODS:
Data were obtained from women enrolled in an open cohort study ...
Home visits during pregnancy enhance male partner HIV counselling and testing in Kenya: a randomized clinical trial.
(University of Nairobi, 2013-08)
BACKGROUND::
HIV testing male partners of pregnant women may decrease HIV transmission to women and promote uptake of prevention of mother-to-child HIV transmission (PMTCT) interventions. However, it has been difficult ...
Delayed initiation of antiretroviral therapy among HIV-discordant couples in Kenya.
(2013)
Timely initiation of antiretroviral therapy (ART) is particularly important for HIV-discordant couples because viral suppression greatly reduces the risk of transmission to the uninfected partner. To identify issues and ...
Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir.
(2013)
Herpes simplex virus-2 (HSV-2) suppression with acyclovir or valacyclovir reduces HIV-1 viral RNA levels; one hypothesis is that HSV-2 suppression reduces immune activation. We measured T cell immune activation markers ...
Traumatic near amputation secondary to hippopotamus attack: lessons for surgeons.
(University of Nairobi, 2013-11)
A 34-y-old man presented to Naivasha District Hospital (NDH) in Naivasha Town, Kenya, with near-complete below-knee amputation and hemorrhage after a hippopotamus attack. Residents from the University of Washington (UW), ...
Partner characteristics predicting HIV-1 set point in sexually acquired HIV-1 among African seroconverters.
(2013)
Plasma HIV-1 RNA set point is an important predictor of HIV-1 disease progression. We hypothesized that inoculum size and HIV-1 exposure prior to HIV-1 transmission may modulate set point. We evaluated predictors of set ...
Immune response to hepatitis B virus vaccination among HIV-1 infected and uninfected adults in Kenya.
(2013)
In studies from high-income countries, human immunodeficiency virus type 1 (HIV-1)-infected persons have diminished responses to hepatitis B virus (HBV) vaccination, compared with HIV-1-uninfected persons, but data from ...
Incident HSV-2 Infections Are Common Among HIV-1-discordant Couples.
(University of Nairobi, 2013)
Background. The synergy between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus type 1 (HIV-1) is well known, but lack of knowledge about the epidemiology of HSV-2 acquisition in HIV-1-discordant couples ...
Biomarker evaluation of self-reported condom use among women in HIV-discordant couples.
(University of Nairobi, 2013)
Self-reported condom use is a commonly collected statistic, yet its use in research studies may be inaccurate. We evaluated this statistic among women in HIV-discordant couples enrolled in a clinical trial in Nairobi, ...