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Now showing items 191-200 of 214
Development and application of a photometric method in quality evaluation of benzimidazole anthelminthics in Nairobi city county.
(University of Nairobi, 2020)
Introduction: Neglected Tropical Diseases (NTDs) are a group of communicable diseases
which are prevalent in the tropics affecting more than one billion people. Helminthiases are
classified among NTDs. Treatment and ...
Perceived determinants of poor outcome of neonatal sepsis at pediatric unit of Kenyatta National Hospital.
(University of Nairobi, 2020)
Introduction: Neonatal sepsis is the most common reason for neonatal admissions in
developing countries. It is also a major cause of neonatal mortality in both developed
and developing countries. Although neonatal sepsis ...
Health-related quality of life and drug therapy problems in patients with sickle cell disease on hydroxyurea at Kenyatta National Hospital.
(University of Nairobi, 2020)
Background: Sickle cell disease is an inherited genetic disorder caused by presence of a
mutated form of hemoglobin. It is estimated that 312,000 babies are born with sickle cell
disease every year, with 90% of these ...
Prevalence of Dolutegravir Associated Hyperglycemia and Its Covariates Among Persons Living With Hiv on Treatment at Kenyatta National Hospital
(University of Nairobi, 2020)
Background
The introduction of dolutegravir based antiretroviral therapy has provided a potent
treatment option for persons living with the human immunodeficiency virus. However,
there is growing evidence from clinical ...
Depression and Its Association With Disease Activity and Quality of Life in Patients With Rheumatoid Arthritis at the Kenyatta National Hospital
(University of Nairobi, 2020)
Background
Rheumatoid arthritis severity can range from self-limiting disease to severe destruction and systemic complications. RA affects patients physically, psychologically and socially. Patients experience pain, joint ...
Molecular Characterization Of Acute And Chronic Hepatitis B Virus Among Patients Attending Selected Hospitals In Kenya
(University of Nairobi, 2020)
Background: Hepatitis B Virus accounts for majority of liver related deaths in the world with 2
billion persons infected worldwide. It’s primarily transmitted through contact with body fluids of
the infected person. The ...
A Retrospective Review of Pharmaceutical Product Dossiers Submitted at the Pharmacy and Poisons Board Between 2010 and 2014
(University of Nairobi, 2020)
Background:
Efficient regulation of pharmaceutical products is crucial in ensuring that the medicines within a specified territory meet the stipulated standards of quality, safety and efficacy. The national medicine ...
Aminoglycoside Trough Levels, Renal Function and Hearing Acuity in Paediatric Patients at Kenyatta National Hospital
(University of Nairobi, 2020)
Aminoglycosides are antibiotics used in pediatrics for the management of severe infections. In resource limited settings, monitoring of drug levels for efficacy and toxicity is minimal and dosing is largely empiric. This ...
Prevalence of proximal tubular dysfunction in ambulatory HIV infected clients on 1st line HAART attending the Mater comprehensive care clinic
(university of Nairobi, 2020)
BACKGROUND
Tenofovir disoproxil fumarate (TDF), is now a widely used component of antiretroviral regimens owing to its high potency and acceptable safety profile. Multiple randomized clinical trials have shown low incidence ...
Characterization of the steady state concentrations and pharmacogenetics of ritonavir boosted atazanavir in Kenyan HIV positive patients.
(University of Nairobi, 2020)
Background
Atazanavir is a protease inhibitor currently recommended for use as a second
line agent in Human Immunodeficiency Virus (HIV) infected patients who have
failed therapy on a first line regimen. The pharmacokinetics ...