Faculty of Health Sciences (FHS): Recent submissions
Now showing items 901-920 of 4298
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Prevalence of Dolutegravir Associated Hyperglycemia and Its Covariates Among Persons Living With Hiv on Treatment at Kenyatta National Hospital
(University of Nairobi, 2020)Background The introduction of dolutegravir based antiretroviral therapy has provided a potent treatment option for persons living with the human immunodeficiency virus. However, there is growing evidence from clinical ... -
Dynamics Of Resistance Plasmids Of Salmonella Enterica Serovar Typhi In Kibera, An Urban Slum Where High Burden Of Typhoid Fever Has Been Described
(University of Nairobi, 2020)Background Multidrug resistance (MDR) in Salmonella enterica serovar Typhi is mainly plasmid-mediated, yet, little is known of the plasmid dynamics in typhoid endemic settings. Methods We used whole genome sequence data ... -
An Assessment Of The Effectiveness Of Adoption Of Alternative Livelihood Strategies On Socio-Economic Wellbeing Of Pastoral Communities In Kajiado County, Kenya
(University of Nairobi, 2020)Pastoralism is a key livelihood source for most people globally and makes an important contribution to Kenya’s GDP. Due to population increase, climatic and weather variations, living conditions have been worsening for the ... -
Magnitude of Post- Urethroplasty Urinary tract infections in Children with hypospadias at Kenyatta National Hospital
(University of Nairobi, 2020)Background: Children who have undergone urethroplasty (reconstructive surgery) procedure for hypospadias are at a higher risk of getting urinary tract infections (UTI). This may be due to urethral scarring following ... -
The burden of depression among ambulatory knee and hip osteoarthritis patients at the Kenyatta National Hospital
(University of Nairobi, 2020)Background: Osteoarthritis (OA) is a degenerative joint disorder arising from biochemical breakdown of articular cartilage and surrounding joint structures. It is the most prevalent type of arthritis and a leading cause ... -
Determination of bacterial isolate profiles, their antimicrobial susceptibility patterns and trends of antibiotic use in patients with open fractures.
(University of Nairobi, 2020)Background: Open fractures are a high burden both locally and globally. Their commonest complication is wound infection, which often escalates to sepsis, osteomyelitis, amputation and even death. The morbidity and mortality ... -
Health-related quality of life and drug therapy problems in patients with sickle cell disease on hydroxyurea at Kenyatta National Hospital.
(University of Nairobi, 2020)Background: Sickle cell disease is an inherited genetic disorder caused by presence of a mutated form of hemoglobin. It is estimated that 312,000 babies are born with sickle cell disease every year, with 90% of these ... -
Development and application of a photometric method in quality evaluation of benzimidazole anthelminthics in Nairobi city county.
(University of Nairobi, 2020)Introduction: Neglected Tropical Diseases (NTDs) are a group of communicable diseases which are prevalent in the tropics affecting more than one billion people. Helminthiases are classified among NTDs. Treatment and ... -
Characterization of the steady state concentrations and pharmacogenetics of ritonavir boosted atazanavir in Kenyan HIV positive patients.
(University of Nairobi, 2020)Background Atazanavir is a protease inhibitor currently recommended for use as a second line agent in Human Immunodeficiency Virus (HIV) infected patients who have failed therapy on a first line regimen. The pharmacokinetics ... -
Assessment of Guideline Concordant Antibiotic Prescribing for Patients With Community Acquired Pneumonia at the Kenyatta National Hospital Medical Wards.
(University of Nairobi, 2020)Background: Pneumonia is a major cause of morbidity and mortality globally. Despite the proven benefits of guideline concordant antibiotic prescribing, research has shown that adherence to clinical guideline recommendations ... -
Parenting experiences of mothers living with chronic mental disorders at Mathari hospital.
(University of Nairobi, 2020)Background: Globally, it is estimated that up to 50% of persons living with mental disorders in developed states and 85% in third world nations are parents with one or more dependent children. Approximately 15.6% of ... -
Perceived determinants of poor outcome of neonatal sepsis at pediatric unit of Kenyatta National Hospital.
(University of Nairobi, 2020)Introduction: Neonatal sepsis is the most common reason for neonatal admissions in developing countries. It is also a major cause of neonatal mortality in both developed and developing countries. Although neonatal sepsis ... -
Outcomes of the healthy heart Africa program on management of hypertensive patients in Nairobi county, Kenya.
(University of Nairobi, 2020)Background: Hypertension is an independent risk factor for developing cardiovascular and renal diseases worldwide. Hypertensive patients in Sub-Saharan Africa have low hypertension awareness, treatment levels and control. ... -
Incidence and patterns of adverse drug reactions in HIV positive patients on isoniazid tuberculosis preventive therapy at Kenyatta National Hospital.
(University of Nairobi, 2020)BACKGROUND: Isoniazid tuberculosis preventive therapy (IPT) is use of isoniazid at a dose of 5mg/kg/day (max 300mg) in adults for a period of 6 to 9 months to prevent reactivation of active tuberculosis (TB). Isoniazid ... -
Determinants of HPV vaccine hesitancy among parents attending Kenyatta National Hospital outpatient clinics.
(University of Nairobi, 2020)Background: Cervical cancer is mainly caused by the oncogenic Human Papilloma Virus (HPV) infection which is prevented among pre-adolescent girls by prophylactic administration of the HPV vaccine prior to sexual debut. ... -
Quality of nursing care for patients with myocardial infarction in accident and emergency Kenyatta National Hospital.
(University of Nairobi, 2020)Background: Every year around the world, 32.4 million cases of myocardial infarctions occurs, most of these occur in lower- and middle-income countries. (WHO, 2013). Additionally, a report by WHO in 2017 showed that 25% ... -
Pregnancy factors affecting birth weight of babies born at the Nairobi Hospital, Kenya.
(University of Nairobi, 2020)Birth weight is a major indicator of neonatal health. Approximately 8% and 4.2% of all babies born in Kenya are classified as low birth weight and macrosomic respectively (UNICEF, 2012; Sanghvi et al., 1989). Bunyoli ... -
Patterns of cervical lymph node metastasis among laryngeal cancer patients presenting at the Kenyatta National Hospital
(University of Nairobi, 2020)Background Regional metastasis to the cervical lymph nodes is common in laryngeal carcinoma and is one of the most important prognostic factors of the disease irrespective of the mode of treatment. Objective To determine ... -
Prevalence and risk factors for helicobacter pylori infection in children aged 3-60 months attending a private and a public hospital clinic in Kenya (Gertrude’s children’s hospital and Githogoro clinic): a comparative study.
(University of Nairobi, 2020)Introduction: Helicobacter pylori is a common bacterial infection globally with the highest infection rates occurring in developing countries. Acquisition occurs in early childhood and the prevalence tends to increase ... -
A Quality Audit on the management of acute ischaemic stroke at Kenyatta National Hospital
(University of Nairobi, 2020)Background Stroke mortality is high and rising in developing countries including Kenya. Eighty four percent of stroke victims in these countries die within 3 years of diagnosis compared to16% of those living in high income ...